Tramadol is a potent analgesic used to treat mild to severe pain. It is available in different dosages which are used for a variety of purposes.
Dosage for Adults
50 to 100 mg immediate-release tablets of Tramadol are taken orally to relieve pain in adults. The immediate-release tablets have a short duration of action of 4 to 6 hours. The maximum Tramadol dosage that can be taken for pain is up to 400 mg per day.
In case of chronic pain, the adult dose of Tramadol should be 25 mg per day initially, for immediate-release tablets. Then the dose should be increased in increments of 25mg for every three days to reach a dosage of 25 mg thrice a day. After that, the dose should be further increased in increments of 50 mg for every three days to reach a dosage of 50 mg thrice a day. The maximum dosage is 400 mg per day.
In case of extended-release tablets, 100 mg should be consumed once a day which can be increased gradually in increments of 100 mg for every five days as the pain persists. The maximum dosage for extended-release tablets is 300 mg per day.
Dosage for the Elderly
In case of people who are 65 to 75 years old or older, the maximum Tramadol dosage for immediate-release tablets is 300 mg per day, to be administered in divided doses. These are ideal for mild to severe pain relief.
Dosage for Children and Teens
In case of people up to 17 years of age, the immediate-release tablets of Tramadol should be administered in doses of 50 to 100 mg after every 4 to 6 hours for instant relief. The maximum Tramadol dosage for immediate-release is 400 mg per day.
Adjustments of Tramadol Dosage In Case Of Compromised Bodily Functions
There are many instances where the above stated doses cannot be taken, for instance, in cases of compromised renal functions, liver functions or at the time of discontinuation of the medicine.
In this case, if the creatinine clearance happens to be less than 30ml per minute, then the intervals between immediate-release Tramadol should be increased to 12 hours and the maximum dosage of Tramadol should be strictly 200 mg per day but no more than that.
The use of extended-release Tramadol tablets is also not recommended in patients with creatinine clearance less than 30 ml per minute. Moreover, patients of hemodialysis should consume only the normal recommended Tramadol dosage because only 7% of the Tramadol gets removed from the body through dialysis.
In case of patients with cirrhosis, the immediate-release Tramadol tablets can be given in doses of 50 mg after every 12 hours. The usage of extended-release Tramadol is however, not recommended in hepatic impairment, such as in severe hepatitis and Child-Pugh class C.
Once the pain has been treated, Tramadol should never be discontinued abruptly. Rather, Tramadol dosage should be decreased gradually before complete discontinuation, otherwise severe withdrawal symptoms can occur.
On the whole, proper Tramadol dosage consumption is vital for the patients, according to their physiology and severity of pain.